Once we integrate all evidence connecting a target to a specific disease, we compute an association score by the means of an harmonic sum. This association score provides an indication of how strong the evidence behind each connection is and can be used to rank genes in order of likelihood as drug targets. The association ID is constructed by using the Ensembl ID of the gene and the EFO ID for the disease (e.g. ENSG00000073756-EFO_0003767). The method returns an association object, which contains the data and summary on each evidence type included in the calculation of the score, as well as the score itself.
643 matches
25 actions
Open Targets Platform REST
25 actions
- Browse API documentationGETv1.0.0
- Browse interactive API documentationGETv1.0.0
- Enrichment analysisPOSTv1.0.0
- Filter available associationsGETv1.0.0
- Filter available evidenceGETv1.0.0
- Find information about a diseaseGETv1.0.0
- Find information about a list of diseasesPOSTv1.0.0
- Find information about a list of targetsPOSTv1.0.0
- Find information about a targetGETv1.0.0
- Find related entitiesPOSTv1.0.0
- Find related entities by diseaseGETv1.0.0
- Find related entities by targetGETv1.0.0
- Find the best hitPOSTv1.0.0
- Get `autocomplete` objects.GETv1.0.0
- Get association by idGETv1.0.0
- Get drug by IDGETv1.0.0
- Get evidence by IDGETv1.0.0
- Get evidence code by IDGETv1.0.0
- Get evidence for a list of IDsPOSTv1.0.0
- Get metrics about the current data releaseGETv1.0.0
- Get statistics about the current data releaseGETv1.0.0
- Get the list of therapeutic areas about the current data releaseGETv1.0.0
- Query expression levelsGETv1.0.0
- Search for a disease or a targetGETv1.0.0
- Search most relevant resultsGETv1.0.0
Other/Open Targets Platform REST
Get association by id
v1.0.0Input
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{
"type": "object",
"properties": {
"id": {
"type": "string"
}
},
"required": [
"id"
],
"additionalProperties": false
}Output
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{
"type": "object",
"additionalProperties": true
}